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. Author manuscript; available in PMC: 2010 Mar 26.
Published in final edited form as: Nat Clin Pract Oncol. 2008 Mar 18;5(5):280–290. doi: 10.1038/ncponc1089

Table 1.

Comparison of the gene signature of epithelial–mesenchymal transition in EpH4 mammary cells and cancer-related gene signatures.

Gene signature and site of origin Gene unicode in EpH4 cells Reference
EMT signatures
HNSCC None Chung et al. (2006)43
Stromal signatures
Fibroblast serum response (human) Fln, Mt1 and Top2a Chang et al. (2004)6
Stromal signature of HNSCC (human) Pcolce Roepman et al. (2006)30
Stromal response of prostate cancer (mouse) Mt2 Bacac et al. (2006)31
Signatures of metastasis–invasion in breast cancer
70-gene prognostic signature CCL2, MT1X and MT2A van‘t Veer et al. (2002)46
‘Invasiveness’ gene signature Ier5 and Fln Liu et al. (2007)92

Abbreviations: EMT, epithelial–mesenchymal transition; HNSCC, head and neck squamous cell carcinoma.