Table 2.
Prevalence of celiac disease in Middle Eastern and North African countries among high risk populations
Country | Population | Method | Confirmation by duodenal biopsy | Prevalence (%) |
Egypt[13] | 150 children with diarrhea and failure to thrive | t-TG12, AEA1 | Yes | 4.7 |
250 children with IDDM | t-TG12, AEA1 | No | 6.4 | |
Saudi Arabia[18] | 123 pts with IDDM | AGA1, ARA1 | Yes (incomplete) | 4.9-8.1 |
Tunisia[19] | 161 pts with Grave disease | AEA1, t-TG1 | Yes (incomplete) | 3.7 |
Turkey[20] | 136 pts with autoimmune thyroiditis | t-TG1 | Yes (incomplete) | 5.9 |
Algeria[21] | 116 children with IDDM | AGA12, AEA1 | Yes | 16.4-20 |
Iran[22] | 100 pts with chronic diarrhea | AGA1, AEA1 | Yes | 19 |
Iran[23] | 825 children with chronic diarrhea | AGA1, AEA1 | Yes | 6.5 |
Iran[24] | 250 pts with IDDM | Total IgA, AEA1 | Yes | 2.4 |
North-Eastern Libya[25] | 243 pts with high clinical suspicion | NR | Yes | 31.7 |
Eastern Saudi Arabia[26] | 145 pts with high clinical suspicion | AEA1, ARA1 | Yes | 4-11 |
Egypt[27] | 25 pts with refractory iron deficiency anemia | AGA2, AEA1, t-TG2, ARA | Yes | 44 |
Turkey[28] | 100 pts with IDDM | AEA1 | Yes | 6 |
Iraq[29] | 40 pts with IDDM | NR | Yes | 15 |
Libya[30] | 234 pts with IDDM | AGA, t-TG, ARA, AEA | Yes | 10.3 |
Tunisia[31] | 348 pts with IDDM | AEA1, t-TG | Yes | 2.6-4 |
Turkey[32] | 122 pts with IDDM | Total IgA, AEA1 | Yes | 2.45 |
IgA;
IgG. IDDM: Insulin dependent diabetes mellitus.