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. Author manuscript; available in PMC: 2010 Mar 27.
Published in final edited form as: Eur J Neurosci. 2005 Aug;22(3):587–594. doi: 10.1111/j.1460-9568.2005.04241.x

Fig. 4.

Fig. 4

Effect of ecto-domain of the rat Nogo-66 receptor (27–310) fused to a rat IgG [NgR(310)ecto-Fc] and methylprednisolone (MP) treatment on axon number caudal to the spinal cord lesion. (A) Treatment with NgR(310)ecto-Fc and MP + NgR(310)ecto-Fc significantly increased the total number of biotin dextran amine (BDA)-labeled axons per section counted 15 mm caudal to the site of injury. (B) The largest increase in axon numbers was observed in the gray matter (GM) compared with ventral white matter (vWM) and dorsal white matter (dWM). *P < 0.05 vs. control, one-way ANOVA with Dunnett’s posthoc test. (C) In treated animals BDA-labeled axons were observed to project from the severed dorsal corticospinal tract into the lesion area. This example was from a rat treated with NgR(310)ecto-Fc and MP.