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. Author manuscript; available in PMC: 2010 Mar 28.
Published in final edited form as: Liver Int. 2008 Mar;28(3):308–318. doi: 10.1111/j.1478-3231.2007.01659.x

Fig. 2.

Fig. 2

Time course of oval cell proliferation (mean ± SE, *P < 0.05 by student's t-test). Normal oval cell density is indicated as a dotted horizontal line. (A) DDC diet – there was a modest increase in oval cell density by day 3, becoming more marked during the recovery period 7–14 days after stopping DDC (stars). (B) Liver irradiation and FAH-null mouse after NTBC withdrawal. There were no significant deviations from normal in oval cell density after focal liver irradiation; FAH-null mouse shows diminished proximal biliary structures and no oval cell proliferation. DDC, 3,5-diethoxycarbonyl-1,4-dihydrocollidine; FAH, fumaryl acetoacetate hydroxylase.