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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: J Infect Dis. 2010 Apr 1;201(7):1081–1083. doi: 10.1086/651198

Table 1. Survival of piglets orally-challenged with 1 × 1010 CFU of EHEC strain 933 and treated IP 48 h after challenge with 2 mg of either Stx2-specific HuMAb 5C12 or Stx1-specific HuMAb 5A4.

Treatment Total no. of piglets No. (%) of survivors2 No. (%) died
PBS1 14 5 (36) 9 (64)
5C12 11 11 (100) 0 (0)
5A4 6 0 (0) 6 (100)
1

PBS group served as a placebo control.

2

Survival rates were significantly different (p values: 0.04 for PBS vs 5C12, 0.01 for PBS vs 5A4, and 0.00008 for 5C12 vs 5A4).