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. Author manuscript; available in PMC: 2011 Feb 26.
Published in final edited form as: Mol Cell. 2010 Feb 26;37(4):529–540. doi: 10.1016/j.molcel.2010.01.015

Figure 5. Impaired UPRmt signaling in animals with reduced ClpX activity.

Figure 5

(A) Representative fluorescent photomicrographs of hsp-60pr∷gfp transgenic worms with a temperature sensitive mutation (zc32) that activates the UPRmt in an otherwise wildtype or d2030.2(tm2183) background. Where indicated wildtype or d2030.2(tm2183) worms were raised on k07a3.3(RNAi) for 3 days.

(B) A corresponding immunoblot of GFP expressed by hsp-60pr∷gfp transgenic worms in whom mitochondrial unfolded protein stress was induced. The worms were treated as indicated in (A).