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EP and CDDO-TFEA alleviate radiation-induced malformations of the body axis (A) Representative micrographs showing dorsal curvature (‘curly-up’; cup) in irradiated (20 Gy) embryos at 72 hpf relative to control non-irradiated fish embryos. (B) Quantification of “curly-up’ incidence in CDDO-TFEA- and EP-treated fish relative to vehicle-treated controls. Asterices denote statistically significant differences between the experimental groups indicated by brackets.
