Table 2.

A summary of the micro-environment specific parameters in the model in dimensional units.

Parameter	Meaning	Value	Reference
Dc	oxygen diffusion constant	1.8 × 10−5cm2 s−1	(Grote et al., 1977)
Dg	glucose diffusion constant	9.1 × 10−5cm2 s−1	(Crone and Levitt, 1984)
Dc	hydrogen ion diffusion constant	1.1 × 10−5cm2 s−1	(Crone and Levitt, 1984)
c0	oxygen background conc.	1.7 × 10−8 mol cm−2	(Anderson, 2005)
g0	glucose background conc.	1.3 × 10−8 mol cm−2	(Walenta et al., 2001)
h0	hydrogen ion background conc.	1.0 × 10−13 mol cm−2 (pH = 7.4)	(Patel et al., 2001)
n0	cancer cell density	1.6 × 105 cells cm−2	(Casciari et al., 1992)
tN	necrotic cell removal rate	5 cell cycles	Estimated