Fig. 1.

CD147 expression is up-regulated on circulating, activated CD4⁺ T cells. PBMCs obtained from human peripheral blood were stained with TC-conjugated anti-CD4 and FITC-conjugated anti-CD147 mAb or isotype control mAb plus PE-conjugated anti-CD25 or anti-HLA-DR. Dot plots show expression of CD147 or isotype versus CD25 expression (A) or HLA-DR (B) after gating on lymphoid CD4⁺ cells. Circled regions denote populations of cells showing CD147^bright expression.