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Analysis of copy number abnormalities at the ESR1 locus using three different acGH platforms
| aCGH platform | No. of probes at ESR1 locus |
Breast tumors | ER status | |||
|---|---|---|---|---|---|---|
| N | Gains (%) | Amplification (%) | ER+ (%) | ER− (%) | ||
| Oligo aCGH2 | 4 | 171 | 13 (8) | 2 (1) | 113 (66) | 58 (34) |
| BAC aCGH4 | 1 | 143 | 5 (3) | 0 (0) | 94 (66) | 49 (34) |
| Agilent 244K aCGH | 33 | 77 | 7 (9) | 2 (3) | 75 (97) | 2 (3) |
