Table 1.
Clinical and laboratory features at admission.
| Characteristics | Neonates with seizures, n = 142 |
Neonates without seizures, n = 1430 |
Crude odds ratio [OR (95 CI)] | P value | Adjusted OR (95% CI) |
P Value |
|---|---|---|---|---|---|---|
| Median (interquartile range) age, days | 6 (2-15) | 4 (0-11) | 1.04 (1.01-1.05) | 0.002 | 1.01 (0.99-1.03) | 0.44 |
| Males (%) | 83 (58.5) | 840 (58.7) | 1.12 (0.75-1.49) | 0.75 | - | - |
| Median weight (kg) [95%CI] | 2.94 [2.46-3.29] | 2.74 [2.04-3.18] | 6.21(1.0-38.7) | 0.05 | 1.00(0.99-1.00) | 0.52 |
| Fever (%) | 75 (52.8) | 502 (35.1) | 2.14 (1.52-3.03) | <0.001 | 1.63 (1.10-2.43) | 0.02 |
| Irritability (%) | 11(7.7) | 25 (1.7) | 4.61 (2.22-9.57) | <0.001 | 2.53 (1.04-6.17) | 0.04 |
| Inability to breast feed (%) | 36 (25.4) | 503 (35.2) | 1.58 (1.08-2.33) | 0.02 | 1.13 (0.71-1.81) | 0.53 |
| Bulging fontanel (%) | 14 (9.9) | 16 (1.0) | 10.22 (4.9-21.1) | <0.001 | 5.94 (2.65-13.30) | <0.001 |
| Hypoglycaemia (%) | 23 (16.2) | 254 (17.7) | 0.91 (0.58-1.44) | 0.69 | - | - |
| Hyponatraemia (%) | 4 (2.8) | 43 (2.9) | 0.92 (0.32-1.59) | 0.87 | - | - |
| Hypernatraemia (%) | 3 (2.1) | 9 (0.6) | 3.34 (0.89-12.47) | 0.07 | - | - |
| Hypokalaemia (%) | 12 (8.1) | 130 (8.9) | 0.90 (0.49-1.67) | 0.75 | - | - |
| Hyperkalaemia (%) | 14 (9.5) | 119 (8.2) | 1.18 (0.66-2.11) | 0.58 | - | - |
| Positive cerebral spinal fluid culture (%) | 9 (8.4) | 11 (1.9) | 14.01 (6.01-32.47) | <0.001 | 14.08 (3.60-55.09) | <0.001 |
| Positive blood culture (%) | 10 (7.0) | 76 (5.3) | 1.32(0.67-2.61) | 0.80 | - | - |