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. 2010 Mar 12;10:96. doi: 10.1186/1471-2407-10-96

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Copyright ©2010 Blattmann et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Chronological course of the therapy trial. HIT/PT will be administered at least one week after the last chemotherapy cycle on 6 days per week. Chemotherapy prior and after HIT/PT is recommended according to standard therapy protocols and is not part of this trial protocol. After the end of HIT/PT, adjuvant chemotherapy can be continued within one week. Diagnostic investigations have to be done at a specific date pre and after HIT/PT. FDG-PET characteristics will be evaluated prospectively.