Table 1.
List of extracellular matrix genes >3-fold downregulated by MFSD2A over-expression in stable-transfected A549 cells.
| Gene symbol | Gene name | Fold-change * | P |
|---|---|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.25 | 1.13E-07 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.07 | 2.57E-02 |
| COL11A1 | collagen, type XI, alpha 1 | 0.10 | 2.60E-02 |
| COL12A1 | collagen, type XII, alpha 1 | 0.09 | 1.01E-03 |
| COL4A2 | collagen, type IV, alpha 2 | 0.25 | 1.78E-07 |
| COL5A1 | collagen, type V, alpha 1 | 0.25 | 1.22E-07 |
| COL6A1 | collagen, type VI, alpha 1 | 0.18 | 4.30E-03 |
| COL7A1 | collagen, type VII, alpha 1 | 0.25 | 3.60E-07 |
| CTGF | connective tissue growth factor | 0.07 | 1.56E-08 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.32 | 1.05E-02 |
| FN1 | fibronectin 1 | 0.16 | 2.53E-02 |
| ICAM1 | intercellular adhesion molecule 1 | 0.25 | 2.18E-07 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.18 | 3.52E-03 |
| ITGA7 | integrin, alpha 7 | 0.19 | 3.96E-03 |
| LAMB3 | laminin, beta 3 | 0.15 | 2.46E-02 |
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.33 | 7.35E-03 |
| MMP10 | matrix metallopeptidase 10 (stromelysin 2) | 0.27 | 1.84E-02 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.16 | 2.17E-03 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) | 0.25 | 3.21E-02 |
| SELL | selectin L | 0.19 | 4.59E-03 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.08 | 1.08E-02 |
| TGFBI | transforming growth factor, beta-induced, 68 kDa | 0.25 | 3.22E-08 |
| THBS1 | thrombospondin 1 | 0.19 | 3.82E-03 |
| THBS3 | thrombospondin 3 | 0.31 | 9.78E-03 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.02 | 6.21E-05 |
* With respect to untransfected A549 cells.