Preclamp GH levels during study visits GP (♦, rhGH + placebo), PP (▪, placebo + placebo), GA (▴, rhGH + acipimox), and PA (•, placebo + acipimox). Data are means ± 1 sem. Repeated-measures analysis showed differences in overnight (2200–0800 h) GH levels across the four study visits (P < 0.0001).