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. Author manuscript; available in PMC: 2011 Apr 1.

Published in final edited form as: Gastroenterology. 2009 Dec 21;138(4):1406–1417. doi: 10.1053/j.gastro.2009.12.010

A) Examples of (a) normal (membranous) and (b) abnormal (cytoplasmic) E-cadherin expression, (c) negative and (d) positive N-cadherin, and (e) negative and (f) positive vimentin expression. B) Example of (a) abnormal (cytoplasmic) E-cadherin expression with concomitant (b) positive N-cadherin expression. C) Quantitative RT-PCR for E-cadherin, N-cadherin, vimentin and PAI-1 mRNA was performed in MSS and MSI human colorectal cancer samples. mRNA levels in MSS tumors were normalized to 1. Columns, average; bars, SEM. *, P<0.05 as compared to MSS tumor samples.

A) Examples of (a) normal (membranous) and (b) abnormal (cytoplasmic) E-cadherin expression, (c) negative and (d) positive N-cadherin, and (e) negative and (f) positive vimentin expression. B) Example of (a) abnormal (cytoplasmic) E-cadherin expression with concomitant (b) positive N-cadherin expression. C) Quantitative RT-PCR for E-cadherin, N-cadherin, vimentin and PAI-1 mRNA was performed in MSS and MSI human colorectal cancer samples. mRNA levels in MSS tumors were normalized to 1. Columns, average; bars, SEM. *, P<0.05 as compared to MSS tumor samples.