Table 2.
Association between EMT markers and clinicopathological factors in colon cancer patients
| E-cadherin | N-cadherin | Vimentin | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Normal n (%) |
Abnormal n (%) |
P | Negative n (%) |
Positive n (%) |
P | Negative n (%) |
Positive n (%) |
P | |
| Differentiation | |||||||||
| Well-Moderate | 69 (72) | 27 (28) | 57 (59) | 39 (41) | 61 (64) | 35 (36) | |||
| Poor | 24 (73) | 9 (27) | 0.93 | 23 (70) | 10 (30) | 0.29 | 28 (85) | 5 (15) | 0.02 |
| Depth of invasion | |||||||||
| T1/T2 | 21 (70) | 9 (30) | 23 (77) | 7 (23) | 25 (83) | 5 (17) | |||
| T3/T4 | 72 (73) | 27 (27) | 0.77 | 57 (58) | 42 (42) | 0.06 | 64 (65) | 35 (35) | 0.05 |
| Node Stage | |||||||||
| Negative | 65 (74) | 23 (26) | 57 (65) | 31 (35) | 66 (75) | 22 (25) | |||
| Positive | 28 (68) | 13 (32) | 0.51 | 23 (56) | 18 (44) | 0.34 | 23 (56) | 18 (44) | 0.03 |
| Stage | |||||||||
| I-II | 64 (74) | 23 (26) | 57 (66) | 30 (34) | 66 (76) | 21 (24) | |||
| III-IV | 29 (69) | 13 (31) | 0.59 | 23 (55) | 19 (45) | 0.23 | 23 (55) | 19 (45) | 0.01 |
| Microsatellite Status | |||||||||
| MSS | 40 (63) | 23 (37) | 33 (52) | 30 (48) | 35 (56) | 28 (44) | |||
| MSI | 53 (80) | 13 (20) | 0.03 | 47 (71) | 19 (29) | 0.03 | 54 (82) | 12 (18) | 0.001 |