Table 4.
PON1 Haplotype frequencies (%) in Mexican-American Mothers (n=431) and Children (n=434)
Haplotypea,b | Mothers | Children |
---|---|---|
GGCLR | 25.1 | 26.4 |
CGTMQ | 15.2 | 14.9 |
CGTLR | 15.2 | 14.7 |
CGTLQ | 14.3 | 14.3 |
GACLQ | 11.2 | 10.8 |
GGCLQ | 6.6 | 6.7 |
GACLR | 5.7 | 6.4 |
CGCLR | 1.7 | 1.3 |
GGCMQ | 0.9 | 1.3 |
GATLQ | 1.4 | 1.1 |
GGCMR | 1.0 | 0.6 |
Polymorphisms in five loci of PON1 gene are listed in the haplotypes using the following order: −909(C/G), −162(A/G), −108(C/T), 55(L/M),192(Q/R)
The eleven haplotypes listed represent 98.4% and 98.5% of the haplotypes present in CHAMACOS mothers and children, respectively. The remaining nine haplotypes (not shown) had frequencies lower than 1%.
PON1 haplotypes were inferred using PHASE 2.1 software.