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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Biochem Pharmacol. 2010 Jan 25;79(11):1640–1647. doi: 10.1016/j.bcp.2010.01.023

Figure 4.

Figure 4

Effect of thymoquinone nanoparticles on TNF-induced NF-κB activation. (A) KBM-5 (1 × 106 cells/mL) cells were treated with indicated concentrations of thymoquinone or thymoquinone nanoparticles for 4 h then co-incubated with TNF (0.1 nM) for 30 min. Nuclear extracts were prepared and the NF-κB activity was examined by EMSA (panel A). (B) Relative NF-κB activation by TNF and its inhibition by TQ and TQ-NP. Data are the representative of three independent experiments. Points, mean (n = 3); bars, S.E. *, P < 0.05; **, P < 0.01 versus untreated cells.