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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Biochem Pharmacol. 2010 Feb 10;79(11):1667–1673. doi: 10.1016/j.bcp.2010.02.002

Figure 2.

Figure 2

Effect of CP-532,903 on fMLP-induced F-actin formation in mouse bone marrow neutrophils. Neutrophils were pretreated with vehicle (A) or 100 nM CP-532,903 (B) for 30 min at 37°C in the presence of 1 unit/ml ADA, and then stimulated with 1 μM fMLP for 30 sec. Cells were stained with FITC-conjugated phalloidin and intracellular fluorescence was quantified by flow cytometry assessing a total of 10,000 cells per sample. Mean ± SEM. *, p < 0.05 versus the vehicle-treated group by Student’s t test, n = 8.