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. 2007 Dec;1(4):173–180. doi: 10.1111/j.1751-228X.2007.00018.x

Table 2.

Testing the Generalist Genes Hypothesis: Correlations Between Reading SNP-Set Scores and Other Measures of Literacy, Math, and Cognitive Abilities

Phenotype SNP set (complete data)a SNP set (missing data option)b
NC English
Speaking and listening r= .048 (p= .060), N= 1,538 r= .051** (p= .001), N= 3,924
Reading r= .079** (p= .002), N= 1,536 r= .078** (p< .001), N= 3,919
Writing r= .088** (p= .001), N= 1,529 r= .072** (p< .001), N= 3,903
English composite r= .083** (p= .001), N= 1,543 r= .077** (p< .001) N= 3,935
NC math
Using and applying r= .109** (p< .001), N= 1,528 r= .072** (p< .001), N= 3,912
Numbers and algebra r= .078** (p= .002), N= 1,526 r= .074** (p< .001), N= 3,909
Shapes, space, and measures r= .086** (p= .001), N= 1,517 r= .071** (p< .001), N= 3,888
Math composite r= .098** (p< .001), N= 1,533 r= .077** (p< .001), N= 3,923
General cognitive ability
Vocabulary r= .045 (p= .090), N= 1,442 r= .050** (p= .005), N= 3,158
Similarities r= .050 (p= .058), N= 1,439 r= .042* (p= .017), N= 3,158
Conceptual Grouping r= .035 (p= .179), N= 1,448 r= .026 (p= .151), N= 3,173
Picture Completion r= .033 (p= .209), N= 1,445 r= .017 (p= .341), N= 3,172
Verbal Composite r= .056* (p= .034), N= 1,434 r= .053** (p= .003), N= 3,145
Nonverbal Composite r= .046 (p= .084), N= 1,445 r= .028 (p= .111), N= 3,169
Composite g r= .066* (p= .012), N= 1,432 r= .052** (p= .003), N= 3,140

Note.NC = National Curriculum; SNPs = single nucleotide polymorphisms.

a

These SNP-set analyses include only those individuals with data for all 10 SNPs.

b

These SNP-set analyses include individuals with missing genotypes replaced with the population mean.

*

indicates significance at .05 alpha level.

**

indicates significance at .01 alpha level.