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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Nat Genet. 2010 Mar 14;42(4):338–342. doi: 10.1038/ng.542

Figure 4.

Figure 4

Clinical and biological characteristics associated with PHF6 mutations in T-ALL. (a) Frequencies of PHF6 mutations in pediatric and adult T-ALL samples. (b) Differential distribution of PHF6 mutations in TLX1/TLX3 positive and negative T-ALL samples. (c) Kaplan-Meier curve of overall survival in pediatric T-ALL patients from DCOG trials ALL7, ALL8 and ALL9 with and without PHF6 mutations. (d) Kaplan-Meier survival curve in adult T-ALL patients with and without mutations in PHF6 treated in ECOG clinical trial ECOG2993.