Table II.

Treatment Attributes and Levels

Treatment Attribute	Levels
Symptoms and activity limitations	Remission: - No pain most days - No more than 1 loose stool per day - Generally feel well - No problems with work or leisure activities Mild Crohn's disease: - Mild pain most days - About 3 diarrhea stools per day - Generally feel below par - Some problems with work and leisure activities Moderate Crohn's disease: - Moderate pain most days or severe pain on some days - About 8 or more diarrhea stools per day - Generally feel poorly - Considerable problems with work and leisure activities Severe Crohn's disease: - Severe pain most days - More than 12 diarrhea stools per day - Generally feel terrible - Unable to engage in work and leisure activities
Serious complications from CD	Treatment prevents all serious complications of CD Treatment reduces some of the serious complications of CD Treatment has no effect on the serious complications of CD
Time between flare-ups	6 months between flare-ups 2 years between flare-ups
Need to take oral steroids	Requires taking steroids Does not require taking steroids
Chance of dying from serious infection within 10 years	None would die 5 patients out of 1,000 (0.5%) would die 20 patients out of 1,000 (2.0%) would die 50 patients out of 1,000 (5.0%) would die
Chance of dying or severe disability from PML within 10 years	None would die or have disability 5 patients out of 1,000 (0.5%) would die or have disability 20 patients out of 1,000 (2.0%) would die or have disability 50 patients out of 1,000 (5.0%) would die or have disability
Chance of dying from lymphoma within 10 years	None would die 5 patients out of 1,000 (0.5%) would die 20 patients out of 1,000 (2.0%) would die 50 patients out of 1,000 (5.0%) would die