Skip to main content
. 2010 Apr 15;137(8):1361–1371. doi: 10.1242/dev.045666

Fig. 5.

Fig. 5.

Expression of AP markers is altered in ptc1–/–; lep–/– otic vesicles. (A-L) Expression of anterior (hmx3, fgf8, pax5), ventral/central (otx1) and posterior (fst1) otic markers. In ptc1–/–; lep–/–, expression of anterior markers is reduced or absent, otx1 expression is reduced, and posterior fst1 expression (arrow, K) is lost in the ear but upregulated in surrounding tissues. (A-H) Lateral views, anterior to left, dorsal to top. (I-L) Dorsal views; anterior to left, lateral to bottom. Scale bars: 50 μm (in left-hand image of each pair).