Figure 6. TLR-specific gene transcription profiles reveal increased expression of TRIF-responsive genes in macrophages from UC patients after stimulation with HkEc.

Macrophages from UC (n = 8) and HC (n = 8) were stimulated for 4 h with HkEc followed by gene array analysis. (A) Volcano plot showing the alteration in expression levels between UC and HC after HkEc stimulation. Only eight genes (p<0.05 (blue line) and fold change >2) demonstrated significantly different expression levels after stimulation (labeled a–h). (B) Identification of the abnormally expressed genes with the corresponding fold change and p-value.