Figure 2.

Resection of pancreatic tumor mass restored the MDCs and PDCs in some subjects. (A) Percentage of MDCs (top) and PDCs (bottom) of total PBMCs in healthy age match controls and pre and post tumor resection in individuals with pancreatic duct adenocarcinoma (PDAC) (B) Pre and post tumor resection levels of MDCs (top) and PDCs (bottom) in individuals with PDAC. (C) Dot plots showing the percentage of MDCs (CD11c+) and PDCs (CD123+) pre and post tumor resection in a subject with PDAC with fully recovered DC populations 12 weeks post surgery. Percent of MDCs (top) and PDCs (bottom) of total PBMCs in healthy age match controls and pre and post resection in individuals with (D) ampullary carcinoma (AC), (E) endocrine carcinoma (EC) and (F) chronic pancreatitis (CP). Statistically significant differences between individuals with pancreatic disease and healthy controls are indicated as; * = p < 0.05, ** = p < 0.005, *** = p < 0.001