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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Stroke. 2010 Jan 21;41(3):563–565. doi: 10.1161/STROKEAHA.109.572339

Table 1.

Results of sensitivity analysis (N94 and N99 shows the size of the cohorts of respective years)

Females Males
N94,N99 log-rank Median (years) N94,N99 log-rank Median (years)
94–96 99–01 94–96 99–01
Base calculation 261,206 0.0009 0.64 0.29 142,115 0.8132 0.39 0.17
1. Approaches to identification of recovery events
Time to recovery (1.5 years) 237,192 0.0049 1.05 0.36 135,109 0.9988 0.69 0.41
Time to recovery (0.5 years) 286,223 0.0043 0.34 0.21 155,129 0.9686 0.24 0.17
Alzheimer’s disease and dementia 261,206 0.0178 0.61 0.41 142,115 0.4345 0.42 0.17
2. Approaches to identification of incident cases
All Medicare sources used 286,221 0.0013 0.64 0.31 159,125 0.6977 0.39 0.24
Keeping not only primary diagnoses 323,269 0.0009 0.49 0.24 182,145 0.4876 0.36 0.09
No requirement of second visit 523,416 0.0111 0.09 0.05 276,242 0.4220 0.05 0.01
Acceptable lag of pre-diagn.=0.5year 261,206 0.0009 0.64 0.29 146,117 0.8363 0.39 0.20
Only 436 ICD-9 code included 228,182 0.0017 0.61 0.25 123,90 0.8276 0.39 0.24
Exclude hemorrhagic (ie, 431) stroke 258,202 0.0016 0.62 0.29 141,109 0.7406 0.39 0.25
Only hemorrhagic (i.e., 431) stroke 13,14 0.5680 0.016 0.063 10,12 0.1711 0.227 0.027
Include ICDs: 430–432 23,28 0.0871 0.112 0.067 20,20 0.6478 0.153 0.114
Exclude not completely covered 229,188 0.0041 0.61 0.27 136,108 0.5108 0.39 0.14
3. Factors of observed heterogeneity
65≤Age≤72 56,43 0.0140 0.61 0.21 31,31 0.4543 0.25 0.32
73≤Age≤84 139,110 0.0096 0.72 0.30 95,66 0.8493 0.39 0.20
85≤Age 66,53 0.4828 0.61 0.46 16,18 0.3374 0.15 0.09
Charlson Index=0 107,77 0.0522 0.61 0.24 55,36 0.9565 0.18 0.23
1≤Charlson Index≤3 120,95 0.0232 0.76 0.36 66,56 0.7897 0.46 0.14
Charlson Index≥4 34,34 0.1317 0.61 0.25 21,23 0.8836 0.79 0.25
Disability group=1 143,128 0.0007 0.60 0.24 97,87 0.4733 0.39 0.13
Disability group=2 47,27 0.0504 1.01 0.21 22,13 0.4767 0.13 0.28
Disability group=3 71,51 0.9775 0.80 0.90 23,15 0.5246 1.32 1.49
4. Censoring strategies
Cases of death are recovery cases 261,206 0.0059 0.50 0.25 142,115 0.4704 0.39 0.16
Cases of death are never recovered 346,278 0.0478 2.61 0.93 194,154 0.5400 1.20 1.17
5. Disenrollment from Medicare and coverage by HMO
All covered by HMO are included 284,215 0.0125 0.61 0.33 149,124 0.8593 0.37 0.17
Fraction of HMO enrollment≤0.3 264,209 0.0015 0.62 0.31 145,118 0.9811 0.39 0.17
6. Study Design effect
Using NLTCS weights 472524, 427500 0.62 0.31 270628, 255493 0.39 0.13