Base calculation |
261,206 |
0.0009 |
0.64 |
0.29 |
142,115 |
0.8132 |
0.39 |
0.17 |
1. Approaches to identification of recovery events |
Time to recovery (1.5 years) |
237,192 |
0.0049 |
1.05 |
0.36 |
135,109 |
0.9988 |
0.69 |
0.41 |
Time to recovery (0.5 years) |
286,223 |
0.0043 |
0.34 |
0.21 |
155,129 |
0.9686 |
0.24 |
0.17 |
Alzheimer’s disease and dementia |
261,206 |
0.0178 |
0.61 |
0.41 |
142,115 |
0.4345 |
0.42 |
0.17 |
2. Approaches to identification of incident cases |
All Medicare sources used |
286,221 |
0.0013 |
0.64 |
0.31 |
159,125 |
0.6977 |
0.39 |
0.24 |
Keeping not only primary diagnoses |
323,269 |
0.0009 |
0.49 |
0.24 |
182,145 |
0.4876 |
0.36 |
0.09 |
No requirement of second visit |
523,416 |
0.0111 |
0.09 |
0.05 |
276,242 |
0.4220 |
0.05 |
0.01 |
Acceptable lag of pre-diagn.=0.5year |
261,206 |
0.0009 |
0.64 |
0.29 |
146,117 |
0.8363 |
0.39 |
0.20 |
Only 436 ICD-9 code included |
228,182 |
0.0017 |
0.61 |
0.25 |
123,90 |
0.8276 |
0.39 |
0.24 |
Exclude hemorrhagic (ie, 431) stroke |
258,202 |
0.0016 |
0.62 |
0.29 |
141,109 |
0.7406 |
0.39 |
0.25 |
Only hemorrhagic (i.e., 431) stroke |
13,14 |
0.5680 |
0.016 |
0.063 |
10,12 |
0.1711 |
0.227 |
0.027 |
Include ICDs: 430–432 |
23,28 |
0.0871 |
0.112 |
0.067 |
20,20 |
0.6478 |
0.153 |
0.114 |
Exclude not completely covered |
229,188 |
0.0041 |
0.61 |
0.27 |
136,108 |
0.5108 |
0.39 |
0.14 |
3. Factors of observed heterogeneity |
65≤Age≤72 |
56,43 |
0.0140 |
0.61 |
0.21 |
31,31 |
0.4543 |
0.25 |
0.32 |
73≤Age≤84 |
139,110 |
0.0096 |
0.72 |
0.30 |
95,66 |
0.8493 |
0.39 |
0.20 |
85≤Age |
66,53 |
0.4828 |
0.61 |
0.46 |
16,18 |
0.3374 |
0.15 |
0.09 |
Charlson Index=0 |
107,77 |
0.0522 |
0.61 |
0.24 |
55,36 |
0.9565 |
0.18 |
0.23 |
1≤Charlson Index≤3 |
120,95 |
0.0232 |
0.76 |
0.36 |
66,56 |
0.7897 |
0.46 |
0.14 |
Charlson Index≥4 |
34,34 |
0.1317 |
0.61 |
0.25 |
21,23 |
0.8836 |
0.79 |
0.25 |
Disability group=1 |
143,128 |
0.0007 |
0.60 |
0.24 |
97,87 |
0.4733 |
0.39 |
0.13 |
Disability group=2 |
47,27 |
0.0504 |
1.01 |
0.21 |
22,13 |
0.4767 |
0.13 |
0.28 |
Disability group=3 |
71,51 |
0.9775 |
0.80 |
0.90 |
23,15 |
0.5246 |
1.32 |
1.49 |
4. Censoring strategies |
Cases of death are recovery cases |
261,206 |
0.0059 |
0.50 |
0.25 |
142,115 |
0.4704 |
0.39 |
0.16 |
Cases of death are never recovered |
346,278 |
0.0478 |
2.61 |
0.93 |
194,154 |
0.5400 |
1.20 |
1.17 |
5. Disenrollment from Medicare and coverage by HMO |
All covered by HMO are included |
284,215 |
0.0125 |
0.61 |
0.33 |
149,124 |
0.8593 |
0.37 |
0.17 |
Fraction of HMO enrollment≤0.3 |
264,209 |
0.0015 |
0.62 |
0.31 |
145,118 |
0.9811 |
0.39 |
0.17 |
6. Study Design effect |
Using NLTCS weights |
472524, 427500 |
|
0.62 |
0.31 |
270628, 255493 |
|
0.39 |
0.13 |