Table 1.
Assessment of the genome-wide TFBS predictions when |W| = 1,000 bp
Chromia TP (PPV) | ||
---|---|---|
TF | Promoters | Enhancers |
CTCF | 319 (16.0%) | 195 (9.8%) |
E2f1 | 1,920 (96.0%) | 618 (30.9%) |
Esrrb | 585 (29.2%) | 491 (24.6%) |
Klf4 | 917 (45.9%) | 351 (17.5%) |
Nanog | 138 (6.9%) | 376 (18.8%) |
Myc (n-Myc + c-Myc) | 1,436 (71.8%) | 167 (8.3%) |
Oct4 | 240 (12.0%) | 208 (10.4%) |
Oct4-Sox2-Nanog | 384 (19.2%) | 431 (21.6%) |
Smad1 | 6 (0.3%) | 95 (4.8%) |
Sox2 | 63 (3.1%) | 235 (11.8%) |
STAT3 | 99 (5.0%) | 82 (4.1%) |
Tcfcp2l1 | 716 (35.8%) | 595 (29.8%) |
Zfx | 1,320 (66.0%) | 219 (10.9%) |
A prediction was considered to be a true positive (TP) if it was within |W| = 1,000 bp of a TF binding peak. The total number of predictions is 2,000.