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. Author manuscript; available in PMC: 2010 Mar 31.
Published in final edited form as: J Infect Dis. 2009 Sep 15;200(6):926–934. doi: 10.1086/605411

Figure 1.

Figure 1

Infection- or vaccine-induced immunity enhance clearance of genital chlamydial infection. Groups of C57BL/6 mice with immunity to chlamydial genital infection due to preinfection (infection-induced immunity) or vaccination with either the Fc fusion protein of the chlamydial major outer membrane protein (Fc-MOMP) or Chlamydia-pulsed interleukin-10 knockout dendritic cells (IL-10KO DCs) (vaccine-induced immunity), as well as control mice, were challenged genitally with mouse pneumonitis (1 × 105 inclusion-forming units [IFUs] per mouse). The course of infection was monitored by periodic swabbing of cervicovaginal vaults, and chlamydiae were isolated in tissue culture, as described in the Materials and Methods. Experiments were repeated 3 times, with 6 mice per experimental group, and Chlamydia IFU values represent means ± standard deviations.