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. Author manuscript; available in PMC: 2011 Mar 2.

Published in final edited form as: Vaccine. 2010 Jan 4;28(10):2236–2242. doi: 10.1016/j.vaccine.2009.12.049

Table 1.

Local Reactogenicity

	1^st Vaccination				2^nd Vaccination
	Total	Grade 1	Grade 2	Grade 3	Total	Grade 1	Grade 2	Grade 3
5 μg
Pain/Tenderness	12/12	9	3	0	11/11	7	2	2
Erythema	2/12	1	1	0	2/11	2	0	0
Swelling	2/12	0	2	0	4/11	0	2	2
Induration	2/12	1	1	0	0	0	0	0
Nodule	0	0	0	0	0	0	0	0
20 μg
Pain/Tenderness	12/12	5	7	0	9/9	6	3	0
Erythema	2/12	2	0	0	4/9	1	2	1
Swelling	3/12	3	0	0	2/9	1	1	0
Induration	3/12	3	0	0	1/9	1	0	0
Nodule	0	0	0	0	1/9	1	0	0
80 μg
Pain/Tenderness	3/4	3	0	0	NA
Erythema	1/4	1	0	0	NA
Swelling	2/4	1	1	0	NA
Induration	1/4	1	0	0	NA
Nodule	0	0	0	0	NA

Maximum observed grade for each volunteer after each vaccination