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. Author manuscript; available in PMC: 2010 Mar 31.
Published in final edited form as: Thromb Haemost. 2009 Dec 18;103(2):426–434. doi: 10.1160/TH09-05-0305

Fig. 1. Pharmacokinetics of IP-administered human solCD39 in mice.

Fig. 1

The activity of solCD39 in murine plasma was measured using our ADPase radio-TLC assay, as described in “Materials and Methods”. The enzymatic activity of each sample was expressed as picomoles ADP metabolized per min per μl plasma. Each data point represents the mean ADPase activity (± SD) in plasma samples from 2-4 mice; values for each plasma sample were obtained from 2-3 separate assays. The dashed line, which signifies the ADPase activity of 17.1 μg/ml solCD39 in murine plasma, is shown as a comparison. SolCD39 in vivo half-life was determined using two phase exponential decay nonlinear regression analyses.