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. Author manuscript; available in PMC: 2010 Mar 31.
Published in final edited form as: Science. 2009 May 15;324(5929):938–941. doi: 10.1126/science.1171396

Fig. 2.

Fig. 2

ERK1/2 are required for the terminal differentiation of GCs during ovulation. (A and B) BrdU staining of WT and Erk1/2gc−/− ovary sections at 8 hours after hCG treatment. Scale bars, 62.5 µm. (C to F) In situ hybridization shows the expression of Cyp11a1 mRNA in ovaries of WT and Erk1/2gc−/− mice at 48 hours after hCG treatment. Histology of the ovaries is shown by hematoxylin staining (C and D); localization of Cyp11a1 mRNA is shown by dark-field images (E and F). Scale bars, 250 µm.