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. Author manuscript; available in PMC: 2010 Mar 31.
Published in final edited form as: Science. 2009 May 15;324(5929):938–941. doi: 10.1126/science.1171396

Fig. 3.

Fig. 3

ERK1/2 extensively regulate the expression of FSH/LH-target genes during ovulation. (A) Summary of gene expression profiling data. Genes regulated more than fourfold between 0 and 4 hours after hCG treatment were defined as LH-target genes; those that failed to respond to hCG in the Erk1/2gc−/− cells were defined as ERK1/2-dependent genes. (B to D) qRT-PCR shows the expression of selected FSH/eCG and LH/hCG target genes in GCs of WT and Erk1/2gc−/− mice after hCG treatment. Error bars denote SD.