Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Mar 26;6(3):e1000830. doi: 10.1371/journal.ppat.1000830

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

(A) Histogram plotting F_ST (±SD) values at 8 neutral (gray bars) and 10 dhps (black bars) microsatellite loci. Asterisk indicates significant values obtained after 1000 random permutations. Populations were defined according to their dhps genotype (i.e. wild type, single, double, or triple mutant) for calculations of the overall (global) F_ST. The overall F_ST for dhps after jackknifing over loci was 0.20 (95% CI: 0.15–0.26) whereas the overall F_ST for 8 neutral loci was 0.01 (95% CI: 0.006–0.019). The difference between F_ST values of dhps and neutral groups was highly significant as assessed by Mann-Whitney U test (Z = 3.55, P = 0.0003). (B) Plot of F_ST versus H_e to disentangle selection on dhps and neutral loci. Black circles represent 10 dhps loci and white diamonds represent 8 neutral loci. The gray shading indicates the region of neutral expectations at a confidence level of 95%. The markers above the gray region are considered to be under directional selection while those inside the gray region are considered to be neutral. The P values (simulated F_ST<sample F_ST) for each locus are given as supporting information (Table S4).