Figure 4.

Expression of Hoxd8, Hoxd9, Myh7, Myh2, Myh1 and Myh4 in quadriceps, gastrocnemius and soleus. Gene expression levels of Hoxd8, Hoxd9, Myh7, Myh2, Myh1 and Myh4 in quadriceps, gastrocnemius and soleus of 20-week LFD and HFD mice. The genes Myh7, Myh2, Myh1 and Myh4 are markers for type I, IIa, IIx and IIb fiber types, respectively. White bars, dashed bars and black bars represent quadriceps, gastrocnemius and soleus, respectively. Bars represent grand mean values of 20-week LFD mice and 20-week HFD mice. *** Indicate significant differences with p < 0.001 obtained with two-way ANOVA