Table 1.
probe set | gene name | gene description | Accession (EntrezID) | Fold change | FDR |
---|---|---|---|---|---|
Strongest up-regulated genes | |||||
15438_at | Hoxd9 | homeo box D9 | 15438 | 7.70 | 0.000 |
15430_at | Hoxd10 | homeo box D10 | 15430 | 7.36 | 0.000 |
15437_at | Hoxd8 | homeo box D8 | 15437 | 4.78 | 0.000 |
21952_at | Tnni1 | troponin I, skeletal, slow 1 | 21952 | 4.46 | 0.005 |
17906_at | Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 17906 | 3.89 | 0.004 |
277898_at | 9830102E05Rik | RIKEN cDNA 9830102E05 gene | 277898 | 3.69 | 0.002 |
19378_at | Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 19378 | 3.61 | 0.000 |
21955_at | Tnnt1 | troponin T1, skeletal, slow | 21955 | 3.56 | 0.024 |
140781_at | Myh7 | myosin, heavy polypeptide 7, cardiac muscle, beta | 140781 | 3.26 | 0.039 |
21924_at | Tnnc1 | troponin C, cardiac/slow skeletal | 21924 | 3.05 | 0.020 |
Strongest down-regulated genes | |||||
21380_at | Tbx1 | T-box 1 | 21380 | -7.27 | 0.000 |
50781_at | Dkk3 | dickkopf homolog 3 (Xenopus laevis) | 50781 | -5.40 | 0.000 |
69219_at | Ddah1 | dimethylarginine dimethylaminohydrolase 1 | 69219 | -2.91 | 0.000 |
53311_at | Mybph | myosin binding protein H | 53311 | -2.66 | 0.002 |
18534_at | Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 18534 | -2.62 | 0.015 |
14311_at | Cidec | cell death-inducing DFFA-like effector c | 14311 | -2.57 | 0.009 |
18616_at | Peg3 | paternally expressed 3 | 18616 | -2.49 | 0.005 |
12583_at | Cdo1 | cysteine dioxygenase 1, cytosolic | 12583 | -2.45 | 0.004 |
246747_at | BC054059 | cDNA sequence BC054059 | 246747 | -1.96 | 0.010 |
20249_at | Scd1 | stearoyl-Coenzyme A desaturase 1 | 20249 | -1.79 | 0.018 |
By microarray analysis we found 161 that were differentially expressed in the gastrocnemius as compared with the quadriceps from mice fed an 8-week LFD. This table shows the ten strongest up-regulated and ten strongest down-regulated genes in the gastrocnemius as compared with the quadriceps (n = 10).