Table 8.
TCP-increase for different sensitivities of PET, high whole prostate dose, different α/β values, calculated α and low γ50(CN + 2 definition)
| α [Gy-1] | α/β [Gy] | γ50 | Det. rate PET [%] | Dose [Gy] | SIB [Gy] | Single dose [Gy] | TCPconv [%] | TCP Increase [%] |
|---|---|---|---|---|---|---|---|---|
| 0.03 | 1.5 | 1.4 | 81 | 78 | 90 | 2 | 84.5 | 9.1 |
| 0.03 | 1.5 | 1.4 | 64 | 78 | 90 | 2 | 84.5 | 7.1 |
| 0.04 | 3.1 | 1.4 | 81 | 78 | 90 | 2 | 84.5 | 8.5 |
| 0.04 | 3.1 | 1.4 | 64 | 78 | 90 | 2 | 84.5 | 6.6 |
| 0.06 | 8.3 | 1.4 | 81 | 78 | 90 | 2 | 84.5 | 7.7 |
| 0.06 | 8.3 | 1.4 | 64 | 78 | 90 | 2 | 84.5 | 6.0 |
Calculation of the TCP-increase after boosting choline PET positive regions within the prostate up to 90 Gy, low homogeneous dose 78 Gy. α/β was set to either Fowler's/Wang's or Valdagni's result, α was analytically determined in order to achieve agreement between calculated TCD50 and TCD50 obtained by Cheung et al. γ50 was again taken from Cheung's data (CN + 2 definition).