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. 2010 Mar 12;7:21. doi: 10.1186/1742-2094-7-21

Figure 3.

Figure 3

Double labeling with an antibody to calbindin, a specific marker of Purkinje cells (PCs), proved that the cellular structures targeted by the patient's CSF IgG correspond to PC somata, PC dendrites (upper panel), and PC axons (lower panel). Anti-calbindin reactivity is depicted in red (AlexaFluor® 568); the patient's antibody in green (AlexaFluor® 488); and yellow color indicates overlay of the two antibodies. Nuclei are shown in blue (DAPI). Note that the patient's antibody spared the PC nucleus.