Table 1.
Baseline Characteristics of the MOPSE Subjects
| OMT Group (n ITT = 130) (n PP = 96) |
LT Group (n ITT = 124) (n PP = 95) |
CCO Group (n ITT = 133) (n PP = 127) |
||
|---|---|---|---|---|
| Sex - no. (%) Male | ||||
| ITT Analysis | 59 (45) | 55 (44) | 60 (45) | |
| PP Analysis | 43 (45) | 39 (41) | 59 (46) | |
| Age (yrs) - mean (SD) | ||||
| ITT Analysis | 73.8 (11.8) | 74.6 (12.5) | 72.8 (12.6) | |
| PP Analysis | 74.4 (12.0) | 74.9 (12.8) | 72.3 (12.6) | |
| Race - no. (%) White | ||||
| ITT Analysis | 122 (94) | 110 (89) | 119 (89) | |
| PP Analysis | 91 (95) | 84 (88) | 114 (90) | |
| Body Mass Index (kg/m2) - mean (SD) | ||||
| ITT Analysis | 27.6 (8.5) | 27.8 (8.9) | 27.4 (8.1) | |
| PP Analysis | 27.5 (7.8) | 26.4 (7.3) | 27.3 (8.3) | |
| Smoking History - no. (%) Current/Former | ||||
| ITT Analysis | Current | 25 (19) | 20 (16) | 34 (26) |
| Former | 41 (32) | 48 (39) | 39 (29) | |
| PP Analysis | Current | 18 (19) | 17 (18) | 32 (25) |
| Former | 27 (28) | 36 (38) | 39 (31) | |
| Current Alcohol Use by Chart Review - no. (%) | ||||
| ITT Analysis | 11 (9) | 17 (14) | 20 (15) | |
| PP Analysis | 4 (4) | 14 (15) | 19 (15) | |
| Comorbidities - no. (%) | ||||
| ITT Analysis | COPD | 51 (39) | 56 (45) | 59 (44) |
| Asthma | 18 (14) | 19 (15) | 11 (8) | |
| CHF | 43 (33) | 41 (33) | 39 (29) | |
| DM | 34 (26) | 33 (27) | 44 (33) | |
| HTN | 83 (64) | 83 (67) | 83 (62) | |
| Dementia | 21 (16) | 15 (12) | 19 (14) | |
| Parkinson's | 2 (2) | 1 (1) | 2 (2) | |
| Stroke | 19 (15) | 21 (17) | 18 (14) | |
| PP Analysis | COPD | 36 (35) | 44 (46) | 57 (45) |
| Asthma | 15 (15) | 15 (16) | 11 (9) | |
| CHF | 33 (32) | 31 (33) | 37 (28) | |
| DM | 26 (25) | 24 (25) | 43 (33) | |
| HTN | 68 (67) | 62 (65) | 80 (62) | |
| Dementia | 16 (16) | 11 (12) | 18 (14) | |
| Parkinson's | 1 (1) | 1 (1) | 2 (2) | |
| Stroke | 15 (14) | 14 (15) | 17 (13) | |
| Origin of Pneumonia - no. (%) Community-acquired (vs. Nursing Home-acquired) | ||||
| ITT Analysis | 105 (81) | 98 (79) | 103 (77) | |
| PP Analysis | 79 (82) | 75 (79) | 99 (78) | |
| Aspiration Risk by Chart Review - no. (%) | ||||
| ITT Analysis | 8 (6) | 13 (11) | 4 (3) | |
| PP Analysis | 5 (5) | 8 (9) | 4 (3) | |
| Pneumonia Severity Index - no. (%) | ||||
| ITT Analysis | Class I-II | 22 (17) | 28 (23) | 23 (17) |
| Class III | 34 (26) | 37 (30) | 38 (29) | |
| Class IV | 52 (40) | 44 (35) | 53 (40) | |
| Class V | 22 (17) | 15 (12) | 19 (14) | |
| PP Analysis | Class I-II | 18 (19) | 23 (24) | 23 (18) |
| Class III | 26 (27) | 27 (28) | 37 (29) | |
| Class IV | 40 (42) | 35 (37) | 50 (39) | |
| Class V | 12 (13) | 10 (11) | 17 (13) | |
ITT = intention-to-treat, PP = per-protocol, OMT = osteopathic manipulative treatment, LT = light-touch treatment, CCO = conventional care only, COPD = chronic obstructive pulmonary disease, CHF = congestive heart failure, DM = diabetes mellitus, HTN = hypertension.