Table 1.
Study | Design | Study drugs
|
Length of treatment (days) | |
---|---|---|---|---|
Prednisolone | Control | |||
Berry 197433 | Crossover | 15 mg | Placebo | 7 |
Boardman 196734* | Crossover | 7.5 mg | Placebo | 7 |
Böhm 19673536 | Crossover | 2.5 mg | Placebo | 8 |
Dick 197037 | Crossover | 10 mg | Placebo; ibuprofen 1200 mg; aspirin 4 g† | 7 |
Gestel 1995632 | Parallel | 10 mg | Placebo | 7‡ |
Jasani 196838 | Crossover | 15 mg | Placebo; ibuprofen 750 mg; aspirin 5 g† | 7 |
Lee 197339 | Crossover | 15 mg | Placebo; aspirin 5 g | 7 |
Lee 19734041 | Parallel | 15 mg | Placebo; aspirin 3.9 g | 14 |
Lee 197442 | Crossover | 10 mg | Placebo; sodium salicylate 4 g | 7 |
Stenberg 199243 | Crossover | 3 mg | Placebo | 5§ |
We included two patients in analysis (excluded by authors because of too little difference in joint size) by assuming that difference in grip strength was 0.
Average of ibuprofen and aspirin used in analysis.
One week data provided by authors.
Each flare treated for 5 days; three randomised patients who were excluded because of poor response to prednisolone in introductory test period included in analysis by assuming that difference between prednisolone and placebo was 0.