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. 2010 Mar 19;5:11. doi: 10.1186/1750-1326-5-11

Table 4.

CSF biomarkers and neuropathological score in relation to UCHL1 allele A-carrier status in AD patients and control subjects

	UCHL1 allele A-carrier status
CSF Biomarker	positive	negative	P-value*
T-tau (pg/ml), Mean ± SD
AD patients	640 ± 368	613 ± 297	0.790
Controls	367 ± 175	381 ± 156	0.528

P-tau₁₈₁(pg/ml), Mean ± SD
AD patients	80.6 ± 35.1	75.3 ± 29.4	0.434
Controls	58.8 ± 16.7	65.7 ± 21.1	0.159

Aβ_1-42(pg/ml), Mean ± SD
AD patients	406 ± 91.5	410 ± 104	0.996
Controls	749 ± 195	703 ± 202	0.246

SPs and NFTs score
Median (25^th-- 75^thpercentiles)
AD patients	7 (5-8)	7 (6-9)	0.495
Controls	2 (0-3.5)	0 (0-2)	0.122

CSF = cerebrospinal fluid, AD = Alzheimer's disease, SPs = senile plaques, NFTs = neurofibrillary tangles, Aβ = β-amyloid, *Mann-Whitney U-test