Table 2.
Correlations between viral IgG titers and clinical and brain MRI parameters
| Baseline |
1 year1 |
5 years2 |
||||||
|---|---|---|---|---|---|---|---|---|
| Serologies | BC | NT2L | NT2L | NNT2L | EDSS | NT2L | NNT2L | EDSS |
| Measles | −0.02 (0.796) | −0.02 (0.799) | 0.05 (0.595) | 0.01 (0.876) | 0.08 (0.372) | −0.01 (0.926) | −0.01 (0.961) | 0.02 (0.859) |
| HCMV | −0.06 (0.455) | 0.03 (0.728) | 0.02 (0.801) | 0.01 (0.950) | 0.07 (0.403) | 0.01 (0.946) | −0.03 (0.767) | 0.12 (0.197) |
| HHV-6 | −0.06 (0.473) | −0.05 (0.559) | 0.05 (0.633) | −0.01 (0.969) | −0.17 (0.044) | 0.13 (0.219) | 0.14 (0.182) | −0.01 (0.962) |
| EBV-VCA | 0.22 (0.009) | 0.27 (0.002) | 0.21 (0.020) | 0.12 (0.161) | 0.15 (0.085) | 0.18 (0.077) | 0.08 (0.438) | 0.14 (0.152) |
| -EBNA1 | 0.30 (0.001) | 0.24 (0.006) | 0.24 (0.012) | 0.22 (0.012) | 0.21 (0.015) | 0.31 (0.003) | 0.23 (0.028) | 0.25 (0.010) |
| -EA | −0.01 (0.979) | −0.01 (0.957) | −0.15 (0.501) | −0.15 (0.478) | 0.08 (0.696) | 0.16 (0.547) | 0.04 (0.888) | −0.19 (0.400) |
Data are expressed as Spearman correlation coefficient (p value).
1
Number of patients with 1 year follow-up: 147.
2
Number of patients with 5 year follow-up: 119. HCMV: cytomegalovirus. HHV-6: human herpesvirus 6. EBV: Epstein-Barr virus. VCA: viral capsid antigen. EBNA1: EBV nuclear antigen 1. EA: early antigen. BC: Barkhof criteria. NT2L: number of T2 lesions. NNT2L: number of new T2 lesions. EDSS: Expanded Disability Status Scale.