Table 3.

EBNA1 IgG titers and risk of conversion to MS defined by Poser and McDonald criteria

Criteria		Univariate			Multivariate*9
	N (%)	HR	95% CI	P value	HR	5% CI	P value
Poser
EBNA1	67 (45.6)	1.7	0.9 – 3.2	0.074	1.2	0.6 – 2.1	0.619
McDonald
EBNA1	87 (59.2)	2.2	1.2 – 4.3	0.003	1.6	0.9 – 3.0	0.128

^*For Poser criteria, Cox regression model was adjusted by baseline Barkhof criteria, oligoclonal bands, sex, and gender. For McDonald criteria, inasmuch as the number of Barkhof criteria is included in the McDonald criteria for conversion to MS, the multivariate analysis was adjusted by oligoclonal bands, sex, and gender but not baseline Barkhof criteria. HR: hazard ratio. 95% CI: 95% confidence intervals.