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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Anal Chem. 2010 Apr 1;82(7):2711–2716. doi: 10.1021/ac1002728

Figure 1.

Figure 1

(A) H & E stained hippocampal brain section from a PSAPP mouse. Scale bar = 500 µm. (B) Hierarchical cluster analysis defining three distinct regions of the hippocampus based on lipid content where the axonal layer is red, the dendritic layer is green, and the somatic layer is blue. Scale bar = 500 µm. (C) Average spectrum from each of the three regions illustrating differences in lipid content when normalized to protein content. Important peak frequencies are indicated. Inset shows the olefinic =CH stretching region (3012 cm−1) from the axonal layer spectrum.