Table 1.
Correlation between LRP16 expression and clinicopathological factors in colorectal cancer n (%)
| Variables |
LRP16 |
Statistical value | |
| Positive group (n = 197) | Negative group (n = 139) | ||
| Gender | |||
| Male | 78 (61.4) | 49 (38.6) | χ2 = 1.460a |
| Female | 39 (52.7) | 35 (47.3) | P = 0.227 |
| Age (yr) | |||
| < 45 | 20 (64.5) | 11 (35.5) | χ2 = 0.640a |
| 45 ≤ n < 60 | 36 (58.0) | 26 (42.0) | P = 0.726 |
| ≥ 60 | 61 (56.5) | 47 (43.5) | |
| Tumor size (cm) | |||
| d < 5 | 68 (50.0) | 68 (50.0) | χ2 = 13.604a |
| 5 ≤ d < 10 | 42 (72.4) | 16 (27.6) | P = 0.001 |
| d ≥ 10 | 7 (100.0) | 0 (0.0) | |
| Tumor location | |||
| Cecum | 5 (55.6) | 4 (44.4) | χ2 = 6.027a |
| Ascending colon | 22 (75.9) | 7 (24.1) | P = 0.304 |
| Transverse colon | 8 (57.1) | 6 (42.9) | |
| Descending colon | 6 (66.7) | 3 (33.3) | |
| Sigmoid colon | 29 (60.4) | 19 (39.6) | |
| Rectum | 47 (51.1) | 45 (48.9) | |
| Histologic differentiation | |||
| Well differentiated | 12 (50.0) | 12 (50.0) | χ2 = 9.210a |
| Moderately differentiated | 56 (50.9) | 54 (49.1) | P = 0.010 |
| Poorly differentiated | 49 (73.1) | 18 (226.9) | |
| Depth of invasion, T stage | |||
| T1 | 2 (28.6) | 5 (71.4) | χ2 = 25.470a |
| T2 | 25 (36.8) | 43 (63.2) | P = 0.001 |
| T3 | 79 (69.9) | 34 (30.1) | |
| T4 | 11 (84.6) | 2 (15.4) | |
| Lymph node metastasis | |||
| LN = 0 | 58 (45.3) | 70 (54.7) | χ2 = 24.735a |
| LN = 1-3 | 43 (78.2) | 12 (21.8) | P = 0.001 |
| LN > 3 | 16 (88.9) | 2 (11.1) | |
| Distant metastasis | |||
| Negative | 107 (56.3) | 83 (43.7) | χ2 = 5.115a |
| Positive | 10 (90.9) | 1 (9.1) | P = 0.027 |
| TNM stage | |||
| I-II | 52 (43.3) | 68 (57.7) | χ2 = 27.088a |
| III-IV | 65 (80.2) | 16 (19.8) | P = 0.001 |
a
P < 0.05, statistically significant. LRP16: Leukemia related protein 16.