Table 3.

Relation of potential risk factors to cardiac end points after adjustment for age and sex, in 2693 white patients with non-insulin dependent diabetes mellitus

Variable	Distribution		Coronary artery disease (n=280)					Non-fatal or fatal myocardial infarction (n=192)						Fatal myocardial infarction (n=79)
	Lower third	Upper third	P value	Estimated hazard ratios for each third*				P value	Estimated hazard ratios for each third*					P value	Estimated hazard ratios for each third
Body mass index (kg/m2)	24.8	29.0	0.65					0.083						0.46
Waist:hip ratio	0.87	0.94	0.89					0.50						0.89
Systolic blood pressure (mm Hg)	125	142	0.0032	1	1.52	1.72		0.027	1	1.44	1.70			0.011	1	1.14	2.17
Diastolic blood pressure (mm Hg)	79	87	0.025	1	1.08	1.45		0.0061	1	1.17	1.72			<0.0001	1	0.79	2.09
Hypertension			0.018	1	1.34			0.022	1	1.40				0.008	1	1.83
Fasting plasma glucose (mmol/l)	7.3	9.7	0.016	1	1.31	1.54		0.13						0.017	1	1.83	2.24
Haemoglobin A1c (%)	6.2	7.5	0.0003	1	1.64	1.78		0.01	1	1.47	1.71			0.0099	1	1.09	2.11
Cholesterol (mmol/l)	4.88	5.77	<0.0001	1	1.79	1.93		0.0086	1	1.62	1.67			0.027	1	1.98	2.01
Low density lipoprotein cholesterol (mmol/l)	3.02	3.89	<0.0001	1	1.48	2.29		0.0002	1	1.44	2.11			0.0043	1	1.06	2.25
High density lipoprotein cholesterol (mmol/l)	0.95	1.15	<0.0001	1	0.87	0.51		0.0085	1	0.84	0.57			0.42
Triglyceride (mmol/l)	1.22	1.87	<0.0001	1	1.63	1.93		0.011	1	1.40	1.72			0.079
Insulin (mU/l)	9.7	15.6	0.16					0.022	1	1.18	1.63			0.86
Exercise (sedentary, moderate, active, fit)			0.54					0.044	1	0.73  0.58  0.74†				0.57
Smoking (never smoked, ex-smoker, current smoker)			0.016	1	1.18	1.55		0.015	1	1.27	1.74‡			0.57

^*Not given for non-significant data.  

^†For the four categories of exercise.  

^‡For the three categories of smoking.