Table 5.
Estimated hazard ratios (95% confidence intervals) for coronary artery disease in 3055 patients, fitting same explanatory variables for all three dependent variables
| Dependent variable | Coronary artery disease | Fatal or non-fatal myocardial infarction | Fatal myocardial infarction |
|---|---|---|---|
| No of patients with event | 335 | 233 | 103 |
| Age (years) | |||
| <50 | 1 | 1 | 1 |
| 50-54 | 1.65 (1.18 to 2.31) | 1.76 (1.15 to 2.70) | 5.56 (2.07 to 14.95) |
| 55-59 | 1.78 (1.29 to 2.46) | 2.41 (1.62 to 3.57) | 8.70 (3.37 to 22.48) |
| ⩾60 | 2.35 (1.71 to 3.23) | 2.80 (1.88 to 4.17) | 13.86 (5.43 to 35.41) |
| Sex | |||
| Women | 1 | 1 | 1 |
| Men | 2.12 (1.65 to 2.73) | 2.62 (1.91 to 3.58) | 4.13 (2.53 to 6.76) |
| Low density lipoprotein cholesterol (mmol/l) | |||
| <3.02 | 1 | 1 | 1 |
| ⩾3.02 to <3.89 | 1.41 (1.05 to 1.90) | 1.41 (1.00 to 2.00) | 1.15 (0.67 to 1.97) |
| ⩾3.89 | 2.26 (1.70 to 3.00) | 2.11 (1.50 to 2.95) | 2.32 (1.41 to 3.81) |
| High density lipoprotein cholesterol (mmol/l) | |||
| <0.95 | 1 | 1 | 1** |
| ⩾0.95 to <1.15 | 0.90 (0.71 to 1.15) | 0.94 (0.70 to 1.26) | 1.16 (0.73 to 1.84) |
| ⩾1.15 | 0.55 (0.41 to 0.73) | 0.65 (0.47 to 0.91) | 0.84 (0.51 to 1.39) |
| Haemoglobin A1c (%) | |||
| <6.2 | 1 | 1 | 1 |
| ⩾6.2 to <7.5 | 1.47 (1.12 to 1.95) | 1.26 (0.91 to 1.75) | 0.98 (0.58 to 1.65) |
| ⩾7.5 | 1.52 (1.15 to 2.01) | 1.42 (1.03 to 1.98) | 1.72 (1.06 to 2.77) |
| Systolic blood pressure (mm Hg) | |||
| <125 | 1 | 1* | 1* |
| ⩾125 to <142 | 1.52 (1.12 to 2.06) | 1.45 (1.01 to 2.08) | 1.22 (0.66 to 2.24) |
| ⩾142 | 1.82 (1.34 to 2.47) | 1.76 (1.22 to 2.54) | 2.36 (1.33 to 4.18) |
| Smoking | |||
| Never smoked | 1 | 1 | 1** |
| Ex-smoker | 1.03 (0.77 to 1.37) | 1.08 (0.75 to 1.54) | 0.65 (0.39 to 1.09) |
| Current smoker | 1.41 (1.06 to 1.88) | 1.58 (1.11 to 2.25) | 1.03 (0.62 to 1.70) |
*
Estimated hazard ratios shown for systolic blood pressure despite diastolic blood pressure being included in stepwise selection.
**
Variable not included in stepwise selection model.