Table 2.
Baseline Measures of Other Known Prognostic Markers by Amino Terminal Fragment of the Prohormone Brain-Type Natriuretic Peptide (NT-proBNP) Quartile Among 987 Individuals With Stable Coronary Heart Disease*
| NT-proBNP Quartiles, pg/mL | |||||
|---|---|---|---|---|---|
| 1 (8.06–73.95) (n = 247) | 2 (74–174.5) (n = 247) | 3 (175.1–459) (n = 247) | 4 (≥460) (n = 246) | P Value† | |
| LVEF, mean (SD), % | 65 (6) | 64 (7) | 61 (10) | 56 (12) | <.001 |
| Diastolic dysfunction | 51 (22) | 77 (33) | 97 (44) | 114 (59) | <.001 |
| Left ventricular mass index, mean (SD) | 87 (18) | 92 (21) | 98 (23) | 115 (32) | <.001 |
| Inducible ischemia | 23 (10) | 39 (17) | 71 (31) | 84 (41) | <.001 |
| Exercise capacity, mean (SD), METs | 8.9 (3.6) | 8.1 (3.2) | 6.7 (2.8) | 5.5 (2.6) | <.001 |
| C-reactive protein, mean (SD), mg/dL | 3.02 (3.81) | 3.34 (5.40) | 5.86 (11.36) | 6.14 (9.66) | <.001 |
| Detectable troponin T | 3 (1) | 3 (1) | 8 (3) | 44 (18) | <.001 |
| NYHA class III or IV | 43 (17) | 45 (18) | 59 (24) | 72 (29) | .004 |
Abbreviations: LVEF, left ventricular ejection fraction; MET, metabolic equivalent; NYHA, New York Heart Association.
*
Values are expressed as number (percentage) unless otherwise indicated.
†
Analysis of variance was used for continuous variables and the χ2 test was used for categorical variables.