Table 1.
Characteristics of 152 Ovarian Cancer Cases and 649 Controls From the Nurses' Health Study
| Characteristic | FRα + | FRα- | Controls |
|---|---|---|---|
| N (%) | 60 (39%) | 92 (61%) | 649 |
| Age at diagnosis, mean (SD) | 63.8 (7.4) | 60.02 (9.5) | n/a |
| Parity, mean (SD)a | 4.3 (1.8) | 3.6 (1.6) | 4.0 (1.62) |
| Oral contraceptive use, ever, N (%) | 24 (40%) | 36 (39%) | 293 (45%) |
| Tubal ligation, ever, N (%) | 8 (13%) | 13 (14%) | 123 (19%) |
| Body mass index in 1990, mean (SD) | 25.5 (4.7) | 24.5 (4.7) | 25.4 (4.6) |
| Histology, N (%)b | |||
| Serous | 42 (55%) | 35 (45%) | n/a |
| Endometrioid | 10 (30%) | 23 (70%) | |
| Mucinous | 1 (7%) | 14 (93%) | |
| Clear cell | 2 (14%) | 12 (86%) | |
| Otherc | 5 (38%) | 8 (62%) | |
| Pd | <0.001 | ||
| Disease stage, N (%) | |||
| I, II | 13 (20%) | 52 (80%) | n/a |
| III, IV | 47 (54%) | 40 (46%) | |
| P | <0.001 | ||
| Morphology, N (%) | |||
| Borderline | 1 (6%) | 15 (94%) | n/a |
| Invasive | 59 (43%) | 77 (57%) | |
| P | 0.004 | ||
a
Among parous women.
c
The histological classification in Table 2 was based on abstraction of the pathology report.
c
Other includes Brenner, carcinosarcoma, mixed, other, or unknown.
d
P - value calculated using Fisher's exact test.