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a: Crystal structure of α-haloacid dehalogenase DehI (PDB code 3bjx). The chain is composed of two homologous regions that form a pseudodimer and are connected by a proline-rich arc. The insert shows a reduced schematic representation of the protein. b: Crystal structure of the smallest knot discovered in an uncharacterized protein (PDB code 2efv). Both pictures were prepared with VMD [38].
