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. 2010 Apr 1;5(4):e9953. doi: 10.1371/journal.pone.0009953

Figure 5. IL-7 regulates food intake after fasting.

Figure 5

(A) Food intake during basal conditions in IL-7- (▪) or PBS- (□) treated C57BL/6 mice (n = 7 per group). Results are expressed as the mean ± SEM of cumulative food intake in g/g of body weight. (B) Animals were overnight-fasted, treated with IL-7 (▪) or PBS (□) before getting free access to food (n = 5 per group). Food intake was measured during the 5 h following re-access to food and was expressed as mean ± SEM of cumulative food intake in g/g of body weight. *p<0.05. (C) Prior to the taste aversion assay, water was removed from animal cages overnight. Taste solution of 5% sucrose was offered for 30 min and mice were either s.c. injected with 0.3 µg of IL-7 (n = 5,•) or PBS as control (n = 4,○), or i.p. injected with 6 mEq of LiCl (n = 5,▪) or NaCl as control (n = 4,□). After injection, animals got free access to water containing 0.5% of sucrose. Sucrose cumulative consumption was individually measured 1 h, 3 h, 6 h and 24 h after injection. Results are expressed as mean of sucrose consumption in ml/body weight in g ± SEM. *p<0.05.